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GLP1 Receptors

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In my memory, the foods available in earlier generations were far more nutritious than what’s available today. In the schools, physical education was mandatory, requiring hours of exercise each week. Although television was in the majority of households, compared to today, we were generally more active. As nutritious options began to disappear with sedentary habits increasing, these two combinations led to significant increase in population-wide weight gain. While there are attempts at managing weight through popular diets, most find these programs difficult to sustain. In search of solutions, science has developed a GLP-1 receptor, which mimics the body’s natural hormones to regulate appetite. The use of these medications has skyrocketed, and they are now widely recognized for their impact on metabolic health. By suppressing appetite and regulating insulin, these drugs offer a powerful remedy for managing weight. But it’s well established that rapid weight loss can lead to the loss ...
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Courage to be Disliked

Part 1: Deny Trauma I just started reading the book, “The Courage to Be Disliked" by Ichiro Kishimi. The book is structured as a series of conversations between a young man and a philosopher whose teachings are rooted in the psychology of Alfred Adler. I am also reading Determinism by Robert Sapolsky. It is fascinating to read them simultaneously because they offer completely opposing perspectives. The first part of “The Courage to Be Disliked” would be entirely rejected by Sapolsky, as one who argues against free will while the other does not. They offer vastly different views on the nature of happiness. According to Adler, the past does not matter. It’s about setting goals and finding the courage to be happy. In the first section of “The Courage to Be Disliked”, the author states that trauma does not exist. When the young man asked, "Wait a minute! Are you denying the existence of trauma altogether?" the philosopher responds adamantly, "Yes, I am." To me, hi...
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Sun and Shadow

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While watching the Korean drama The Veil, I found myself struggling to keep pace with its plot transitions. In seeking some clarity, I turned to Google Gemini, which revealed a profound metaphor flowing throughout all the plot references: a dynamic relationship between the Sun and the Shadow. The metaphor reveals that the Sun represents the state—a beacon of light meant to protect the public—yet one that can become dangerously blinding. When the Sun grows too powerful, it obscures the damages it inflicts, allowing leaders to believe that any action, even murder is justified. Then, there are the "Shadows," who exist solely to serve the light, possessing no autonomy or objectivity of their own. This power dynamic serves as the catalyst for the show’s most intense conflicts, particularly when a shadow is forcibly severed from the light. The antagonist Baek Mo-sa, exemplifies this trauma. Once a loyal agent, his abandonment leaves him seeking vengeance against the very Sun he on...
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